MITRAL VALVE DISEASE
Mitral Regurgitation (MR) accounts for the vast majority of all mitral valve diseases.1 It has a prevalence of approximately 2% in the general population and is more common in the elderly population.3 Approximately 10% of people over the age of 70 have clinically meaningful MR.5
If left untreated, MR can lead to Heart Failure (HF), or deterioration of pre-existing HF, resulting in an increased number of hospital admissions and a substantial cost burden to health systems.6,8
MR is a progressive disease, and patients may remain asymptomatic even when the condition has become severe, as compensatory mechanisms develop.11
In some cases, the following symptoms may be experienced:9,10,18
ECHOCARDIOGRAPHY is the basis for diagnosing Valvular Heart Disease (VHD), including MR.16
CARDIAC MAGNETIC RESONANCE (CMR) is a valuable diagnostic tool, especially in patients with limited echo quality, those whose MR severity is unclear, or those who require an evaluation of the myocardial anchoring of the atrioventricular valves.20
COMPUTED TOMOGRAPHY (CT) provides a detailed image of the valve anatomy, especially of the systolic and diastolic ventricle geometry. This information can be valuable for planning a catheter-based intervention.20
The diagnostic pathway of MR has changed over the past few years to align with new treatment options available with regard to transcatheter interventions.
Besides evaluating clinical symptoms like nausea and fatigue, auscultation of the heart is key to diagnosing MR and a detailed pre-operative characterization
of the mitral valve is key to procedural success.20
Connext
Hub
Hub
TV
Transcatheter Mitral Valve implant
T-TEER: Transcatheter Tricuspid Valve Repair - cases, tips, and tricks
T-TEER: echo procedural approach
T-TEER: patient selection and current evidence
M-TEER: primary and secondary Mitral Regurgitation - cases, tips and tricks
M-TEER: echo procedural approach
M-TEER: patient selection and current evidence
Anatomical overview of the AV Valves
Screening Transmission | Mitral focus
TriClip - AVVS 1 year 1 minute Tricuspid - Video
HUB
Epic Mitral – 10-Year Clinical Outcomes
ACC 2023: COAPT™ trial
Tendyne™: 6-Year Outcomes
PCRLV 2021: Transcatheter mitral valve replacement
EuroEcho 2021: MR Treatment (Patient)
ESC 2022: FMR
EuroEcho 2021: MR Treatment (Evidence)
TCT 21: EXPAND G4
ESC 2021: HF & VHD Guidelines
EXPAND Study: Data overview
References
- Lung B, Baron G, Butchart EG, et al. A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease. Eur Heart J.
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- American Heart Association. Problem: Mitral Valve Regurgitation. 2016. Available at: www.heart.org/en/health-topics/heart-valve-problems-and-disease/heart-valveproblems-and-causes/problem-mitral-valve-regurgitation (last accessed: March 2023).
- Spieker M, Kelm M, Westenfeld R. Moderne Diagnostik der Mitral- und Trikuspidalklappe – was ist wirklich notwendig? Aktuelle Kardiologie. 2017;6:265–70.
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