MITRAL VALVE DISEASE
Mitral Regurgitation (MR) accounts for the vast majority of all mitral valve diseases.1 It has a prevalence of approximately 2% in the general population and is more common in the elderly population.3 Approximately 10% of people over the age of 70 have clinically meaningful MR.5
If left untreated, MR can lead to Heart Failure (HF), or deterioration of pre-existing HF, resulting in an increased number of hospital admissions and a substantial cost burden to health systems.6,8
Transcatheter edge-to-edge repair (TEER) is a minimally invasive option:
Overall, many patients in need of valve reconstruction or replacement do not undergo surgery because of high perioperative risk. Transcatheter Mitral Valve repair (TMVr) provides an alternative minimally invasive technique for repair of MR via a percutaneous approach, thus avoiding the need for (open heart) surgery.6
PRIMARY MITRAL REGURGITATION (PMR)
TEER may be considered in symptomatic patients who fulfil the echocardiographic criteria of eligibility, are judged inoperable or at high surgical risk by the Heart Team and for whom the procedure is not considered futile (IIb B)17
SECONDARY MITRAL REGURGITATION (SMR)
TEER with the MitraClip™ System is the best evidenced therapy in this indication. TEER should be considered in selected symptomatic patients, not eligible for surgery and fulfilling criteria suggesting an increased chance of responding to the treatment (IIa).17
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M-TEER: echo procedural approach
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ACC 2023: COAPT™ trial
Tendyne™: 6-Year Outcomes
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EuroEcho 2021: MR Treatment (Patient)
ESC 2022: FMR
EuroEcho 2021: MR Treatment (Evidence)
ESC 2021: HF & VHD Guidelines
EXPAND Study: Data overview
References
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